Mayes County is located in the heart of Northeast Oklahoma. With a population of just under 50,000, Mayes County is made up of the following cities and towns:

• Pryor
• Locust Grove
• Adair
• Chouteau
• Salina
• Spavinaw
• Langley
• Strang
• Pensacola
• Disney
• Sportsmen Acres

The Mayes County Courthouse is located in Pryor, the county seat. In the court house resides the County Commissioners, County Clerk, County Assessor, and the County Treasurer.

​Mayes County is known for its abundant resources. With access to over 2500 miles of lakeshore, the county is able to support businesses and companies such as GRDA and Google.